GSTs also catalyze glutathione dependent isomerization reactions required for the synthesis of several prostaglandins and steroid hormones and the catabolism of tyrosine, additional GST physiological functions, overview metabolism - glutathione S-transferase P1-1 is one of the most important members of phase II detoxification enzyme family which catalyzes the conjugation of glutathione with broad substrates such as chemotherapeutic agents GSTA4_HUMAN 222 0 25704 Swiss-Prot - 22000 - 2 * 22000, SDS-PAGE 24300 - x * 24300, recombinant His6-tagged wild-type GSTZ1-1, SDS-PAGE 25000 - 2 * 25000, basic isoenzyme, SDS-PAGE 25200 - 2 * 25200, form I-XII, SDS-PAGE 25600 - 2 * 25600, form XIII, SDS-PAGE 25630 His-tagged wild type enzyme, calculated from amino acid sequence
Notably, GSH levels were independent factors for predicting the PFS and OS of OC patients
(PubMed) Traber MG
This hormone is not readily degraded by DPP-4 to GLP-1 in the human body and can act for 12 h or longer
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